{"id":6692,"date":"2024-05-08T08:31:49","date_gmt":"2024-05-08T08:31:49","guid":{"rendered":"https:\/\/ledtechno.p1.appoint.be\/?p=6692"},"modified":"2024-11-07T16:02:50","modified_gmt":"2024-11-07T15:02:50","slug":"maximize-cell-growth-with-cornings-hyperstack-cell-culture-vessels","status":"publish","type":"post","link":"https:\/\/www.ledtechno.be\/en\/maximize-cell-growth-with-cornings-hyperstack-cell-culture-vessels\/","title":{"rendered":"Maximize Cell Growth with Corning\u2019s HYPERStack Cell Culture Vessels"},"content":{"rendered":"\r\n

A simple operation<\/strong> based on gas exchange<\/strong> over the gas-permeable film<\/strong> provides up to 5 times more cell growth surface area<\/strong> compared to vessels with a similar footprint.<\/p>\r\n\r\n\r\n\r\n

What is Corning\u2019s High Yield PERformance (HYPER) Platform?<\/strong> The HYPERStack cell culture vessel combines the best of two Corning products: the Corning CellSTACK and the Corning HYPERFlask.<\/p>\r\n\r\n\r\n\r\n

Utilizing gas-permeable film technology<\/strong>, integrated into the spatial footprint of the CellSTACK vessel, the HYPERStack platform becomes one of the most efficient<\/strong> and scalable adherent cell culture vessels<\/strong> available today.<\/p>\r\n\r\n\r\n\r\n

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Video with explanation<\/a><\/div>\r\n<\/div>\r\n\r\n\r\n\r\n\r\n\r\n

Key Benefits and Features:<\/strong><\/p>\r\n\r\n\r\n\r\n

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  • More cells<\/strong> \u2013 provides up to 5 times the growth surface<\/strong> of a traditional cell culture vessel with a similar footprint<\/li>\r\n\r\n\r\n\r\n
  • Closed system<\/strong> \u2013 eliminates open fluid manipulations<\/li>\r\n\r\n\r\n\r\n
  • Scalable product<\/strong> \u2013 Various sizes support scale-up and scale-out<\/strong><\/li>\r\n\r\n\r\n\r\n
  • Ergonomic design<\/strong> \u2013 easier manipulation with handling equipment and accessories<\/li>\r\n\r\n\r\n\r\n
  • Fixed media volume<\/strong> \u2013 0.2 ml\/cm2 fills the vessel for less volumetric waste<\/li>\r\n<\/ul>\r\n\r\n\r\n\r\n

    CORNING\u00ae HYPERSTACK\u00ae CELL CULTURE VESSELS IMPROVE SCALE-UP EFFICIENCY.<\/strong><\/p>\r\n\r\n\r\n\r\n

    (A)<\/strong> Final expansion of Human Mesenchymal Stem Cells in Corning HYPERStack 12-layer or control T-flask cell culture vessels with Corning CellBIND\u00ae surface treatment using hMSC medium. (B)<\/strong> Total Corning HYPERStack vessel yields of Vero cell cultures were 4 times larger<\/strong> than yields of Corning CellSTACK vessels with similar cubic footprints. (C)<\/strong> Corning HYPERStack vessels generated significantly more infectious adenoviral particles<\/strong> than stacked vessels with a similar cubic footprint. Total infectious adenoviral particles were calculated based on titers and the volume of each fraction (cells and medium). (D)<\/strong> Corning HYPERStack vessels generated significantly more infectious lentiviral particles<\/strong> compared to stacked vessels with a similar cubic footprint. Paired t-test, p <0.05, N=3.<\/p>\r\n\r\n\r\n\r\n

    THE TWO TYPES:<\/strong><\/p>\r\n\r\n\r\n

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