A simple operation based on gas exchange over the gas-permeable film provides up to 5 times more cell growth surface area compared to vessels with a similar footprint.
What is Corning’s High Yield PERformance (HYPER) Platform? The HYPERStack cell culture vessel combines the best of two Corning products: the Corning CellSTACK and the Corning HYPERFlask.
Utilizing gas-permeable film technology, integrated into the spatial footprint of the CellSTACK vessel, the HYPERStack platform becomes one of the most efficient and scalable adherent cell culture vessels available today.
Key Benefits and Features:
- More cells – provides up to 5 times the growth surface of a traditional cell culture vessel with a similar footprint
- Closed system – eliminates open fluid manipulations
- Scalable product – Various sizes support scale-up and scale-out
- Ergonomic design – easier manipulation with handling equipment and accessories
- Fixed media volume – 0.2 ml/cm2 fills the vessel for less volumetric waste
CORNING® HYPERSTACK® CELL CULTURE VESSELS IMPROVE SCALE-UP EFFICIENCY.
(A) Final expansion of Human Mesenchymal Stem Cells in Corning HYPERStack 12-layer or control T-flask cell culture vessels with Corning CellBIND® surface treatment using hMSC medium. (B) Total Corning HYPERStack vessel yields of Vero cell cultures were 4 times larger than yields of Corning CellSTACK vessels with similar cubic footprints. (C) Corning HYPERStack vessels generated significantly more infectious adenoviral particles than stacked vessels with a similar cubic footprint. Total infectious adenoviral particles were calculated based on titers and the volume of each fraction (cells and medium). (D) Corning HYPERStack vessels generated significantly more infectious lentiviral particles compared to stacked vessels with a similar cubic footprint. Paired t-test, p <0.05, N=3.
THE TWO TYPES:
